How many acceptable words could one make using this combination of letters?You could make 2 words all in all.
What's the biggest word you can derive from the combination specified?The word 'odwyer' contains 6 characters.
What is the highest score you can get in Scrabble using this list of words with 'dwy' in them?2 combinations possible, you're only practical choice is 'dwyka' which totals 16 points.