Which word in particular from this list contains the largest number of letters?'Antiorthodoxy' contains 13 letters, and is the longest word that's possible to make from the specified combination.
How many words could one make using this combination of letters?On this page of words beginning with 'a' and ending with 'oxy', there are 8 brilliant entries that are possible.
What is the highest scoring word in Scrabble you can play for ?You could make 'alkyloxy' which gets 25 points.