Which word on this page ranks as the most popular?The most popular word for the combination you searched is 'upon'.
What word that has 'u' in and ends with 'on' is the most unique?By far the most unusual word from this list is 'dijudication'. The traditional definition of 'dijudication' is as follows: "The act of dijudicating; judgment. [R.] Cockeram.". Source Cambridge Dictionary.
How many letters does the largest word from this page consist of?Consider 'preobtrudingpreobtrusion'
In total, how many words are possible to make using these specific combinations of letters?On this page of words containing 'u' and ending with 'on', you have 3,122 combinations that are possible in total.
What's the highest scoring word you can play in Scrabble ?Given there are plenty of words from which to select, your best bet is to go for 'squaxon' which scores 23 points.